HARM REDUCTION

PUBLIC HEALTH · STANDALONE PORTAL

Drug Harm Reduction Portal

Temporary standalone public health resource. Evidence-based safety information with no marketplace links, no access mirrors, and no onion addresses.

⚠ MEDICAL EMERGENCY

Call 911 (US) / 999 (UK) / 112 (EU) immediately if someone is unresponsive or not breathing.

Never Use Alone hotline (US): 1-800-484-3731 — stay on the line. Naloxone reverses opioid overdose.

Core Principles

01 — TEST

Use reagent kits and fentanyl test strips before any use. Contamination is documented across many drug categories.

02 — START LOW

Begin with 10–20% of your intended dose. Wait for full onset before considering more.

03 — NEVER ALONE

Have a trusted person present. If alone is unavoidable, call Never Use Alone: 1-800-484-3731.

04 — NALOXONE

Keep naloxone (Narcan) accessible. Available OTC at many pharmacies. Train anyone nearby how to use it.

05 — COMBINATIONS

Opioids + benzodiazepines + alcohol multiply respiratory depression risk. Check TripSit Combo Chart.

06 — OD SIGNS

Opioids: slow/stopped breathing, blue lips, unresponsive. Stimulants: chest pain, seizures, extreme agitation. Call emergency services if unsure.

Opioid Overdose Response

1
CALL EMERGENCY SERVICES

Dial 911 (US), 999 (UK), or 112 (EU) immediately. Good Samaritan laws protect callers in most US states.

2
ADMINISTER NALOXONE

Nasal spray: one spray per nostril. Repeat after 2–3 minutes if no response. Naloxone wears off in 30–90 minutes.

3
RESCUE BREATHING

If not breathing: tilt head back, give one breath every 5 seconds until breathing resumes or EMS arrives.

4
RECOVERY POSITION

Once breathing, place on side. Stay until paramedics arrive — re-overdose is possible as naloxone wears off.

Substance Profiles

MDMA

Test with Marquis. Dose: 75–120mg. Hydrate (~500ml/hour if active). Never combine with MAOIs or SSRIs. Space use by 3+ months.

MODERATE
OPIOIDS

Extreme overdose risk. Always use fentanyl test strips. Never use alone. Keep naloxone accessible. Never combine with alcohol or benzos.

EXTREME
STIMULANTS

High cardiac risk. Test for fentanyl contamination. Never mix cocaine with alcohol (creates cocaethylene).

HIGH
CANNABIS

Low physical toxicity. Edibles: delayed onset 1–3 hours — never redose early. Concentrates can trigger anxiety.

LOW
PSYCHEDELICS

Low physical toxicity. Primary risks are psychological. Have a trip sitter. Avoid if history of psychosis. Test LSD with Ehrlich.

LOW-MOD
KETAMINE

Bladder damage from chronic use. Do not combine with CNS depressants. Avoid driving. Use saline rinse if insufflating.

MODERATE

Public Health Resources

FAQ

What is this harm-reduction portal?

A temporary standalone educational resource focused on reducing drug-related harms. It contains no marketplace links, access mirrors, or onion addresses.

Is this medical advice?

No. Information is sourced from public health organizations for educational purposes. In an emergency, call your local emergency number immediately.

Where can I get naloxone?

Naloxone (Narcan) is available without prescription at most US pharmacies and through local harm reduction programs. Visit nextdistro.org for mail-order options.

How do I test for fentanyl?

Dissolve a small sample in water, dip a fentanyl test strip for 15 seconds. One line = fentanyl detected. Two lines = not detected in this sample. Strips available from DanceSafe and harm reduction programs.